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Fractionation of Nanoparticles by Preparative Gel Electrophoresis – subproject of the SPP 2045

Contact person: Matthäus Barasinski

Summary of the project:
Monodisperse nanoparticles (NP) with completely uniform properties regarding size and morphology are essential already today for optical (plasmonic) applications. In the future, such particles will be necessary for many further areas. For example, in the field of medicine or for self-assembly processes these uniform NP promise a high-precision mode of action and structures with highest precision, respectively.
Since the required narrow particle size distribution or monodispersity is not reached with conventional methods, this subproject shall investigate the fractionation of these synthesized particles with preparative gel electrophoresis. Thereby, the NP are separated spatially in an appropriate gel due to their different electrophoretic mobilities.

Figure: Migration distances of SiO2 nanoparticles with different particle sizes

Objectives and tasks of the iPAT:

  • Synthesis of SiO2 and ZnO NP with subsequent surface modification by ligands
  • Separation of NP by electrophoretic experiments
  • Characterization of the separated particle fractions by TEM and SAXS
  • Understanding of particle-gel-interactions
  • Construction of an electrophoretic chamber for the establishment of a multidimensional separation by particle size and morphology
  • Modelling and simulation of the separation process

  • Team Members

    Current Projects

    Quanomet, Junior Research Group “Nanofluidics & Particle Manipulation” more

    Processing of conjugated nanoparticle hybrid systems for use in biomedical diagnostics more

    Fractionation of Nanoparticles by Preparative Gel Electrophoresis subproject of the SPP 2045 more

    Advanced lithium-sulfur battery concepts for aviation (aero-LiS-SE) more

    Principles of nanoscale matrix additives for fibre composite more

    Nanoscale drug carrier systems as therapeutics for targeted tumor therapy more

    Small Angle X-ray Scattering as Metrological Instrument – A Correlation Study on the Optical Properties of Semiconductor Nanoparticles as ubiquitous Measure of Particle Size more

    Fractionation of Nanoparticles by Preparative Gel Electrophoresis more

    Thin nanoparticle films for cathode composites in all solid state batteries more

    ElektroBak – Innovative Materials and Concepts for Microbial Electrochemical Systems more

    Characteristics of a nanoparticulate coating based on the process chain more

    Finished Projects
    Synthesis and processing of tailored AZO nanocrystals more

    Preparation of multifunctional nanocomposite thin films made of nanosized building blocks more

    Process technology of the synthesis of metal oxide nanoparticles by nonaqueous sol gel methods more

    Biocompatible iron-oxide nanoparticles for the in-situ magnetic separation of bioproducts more

    Small-Molecule Stabilization of ITO Nanoparticles more

    AiF – CleanCoat: Development of transparent, photocatalytically active coatings on polymer substrates with long-term stability more

    Protein purification with functionalized magnetic nanoparticles more